Martin D. Burke、1976年2月5日- 是、美国的有机化学家。伊利诺伊大学厄巴纳-香槟分校教授。
经历
1998 约翰霍普金斯大学 毕业（Henry Brem教授、Gary H. Posner教授）
1998-2005 哈佛大学医学院 MD
1999-2003 哈佛大学・霍华德·休斯医学研究所 PhD（Stuart Schreiber教授）
2005 伊利诺伊大学厄巴纳-香槟分校 助教授
2009 伊利诺伊大学厄巴纳-香槟分校 兼职教授
2009 霍华德·休斯医学研究 Early Career Scientist
2011 伊利诺伊大学厄巴纳-香槟分校 副教授
2014 伊利诺伊大学厄巴纳-香槟分校 教授
获奖经历
2014 Thieme-International Union of Pure and Applied Chemistry (IUPAC) Prize in Synthetic Organic Chemistry
2014 American Asthma Foundation Scholars Award
2014 Hirata Gold Medal, Japan
2014 International Organic Chemistry Foundation Lectureship Award, Japan
2013 Kavli Foundation Emerging Leader in Chemistry Award, American Chemical Society
2013 Elias J. Corey Award for Outstanding Original Contribution in Organic Synthesis by a Young Investigator, American Chemical Society
2013 University of Illinois Innovation Discovery Award
2012 Novartis Chemistry Lectureship: Basel, Horsham, Shanghai, Singapore, San Francisco, and Cambridge
2011 Arthur C. Cope Scholar Award, American Chemical Society
2011 Teacher Ranked as Excellent, UIUC Center for Teaching Excellence
2010 Bristol-Myers Squibb Lectureship at Harvard University
2010 Frontiers in Chemistry Lectureship at The Scripps Research Institute
2010 Novartis Lectureship at The University of California Berkeley
2009 Howard Hughes Medical Institute Early Career Scientist
2009 Alfred P. Sloan Foundation Research Fellowship
2009 Bristol-Myers Squibb Unrestricted Grant in Synthetic Organic Chemistry Award
2009 Eli Lilly Grantee Award
2009 AstraZeneca Excellence in Chemistry Award
2009 Amgen Young Investigator Award
2009 Bristol-Myers Squibb Lectureship at Princeton University
2009 Thieme Chemistry Journals Award
2008 Teacher Ranked as Excellent, UIUC Center for Teaching Excellence
2008 Arnold and Mabel Beckman Foundation Young Investigator Award
2008 “World’s 35 Top Innovators Under 35” Technology Review Magazine
2008 National Science Foundation CAREER Award
2008 “Scientist to Watch” The Scientist Magazine
2007 Teacher Ranked as Outstanding, UIUC Center for Teaching Excellence
2006 Teacher Ranked as Excellent, UIUC Center for Teaching Excellence
2005 ACS Petroleum Research Foundation Type G Award
2005 Camille and Henry Dreyfus New Faculty Award
2005 Henry Asbury Christian Award, Harvard Medical School
2003 National Institutes of Health Medical Scientist Training Program Fellowship
2000 Howard Hughes Medical Institute Predoctoral Fellowship
1998 Hunterian Research Award – Johns Hopkins Department of Neurosurgery
1997 Phi Beta Kappa – Junior Year, Johns Hopkins University
1997 Howard Hughes Undergraduate Research Fellowship – Johns Hopkins University
1997 Provost’s Undergraduate Research Award – Johns Hopkins University
1994-1998 Dean’s List – Johns Hopkins University
1994-1998 Beneficial Hodson Scholar – Johns Hopkins University
1994-1998 Maryland Distinguished Scholar
研究概要
应用MIDA硼酸酯连续构筑骨架法的开发[1]
硼酸N-甲基亚胺基二醋酸(MIDA)酯是在各种化学条件下能够稳定存在的硼酸保护基。比如无保护的硼酸在Suzuki-Miyaura反应下发生偶联反应，而MIDA硼酸酯则不反应。
利用它的这个特性，用带有MIDA硼酸酯做机构单元，各类偶联反应→脱保护重复进行，便轻松实现了复杂化合物的简易合成策略。以下例子就是用该方法成功合成天然产物青霉素。[2]
还有2015年，将这个方法的特性最大限度的活用，成功开发了“一键”就可自动合成复杂有机化合物的装置。[3]。
相关动画
相关文献
- Gillis, E. P.; Burke, M. D. Aldirchimica Acta 2009, 42, 17.
- Woerly, E. M.; Cherney, A. H.; Davis, E. K.; Burke, M. D. J. Am. Chem. Soc. 2010, 132, 6941. doi: 10.1021/ja102721p
- Li, J.; Ballmer, S. G.; Gillis, E. P.; Fujii, S.; Schmidt, M. J.; Palazzolo, A. M. E.; Lehmann, J. W.; Morehouse, G. F.; Burke, M. D. Science 2015, 347, 1221. DOI:10.1126/science.aaa5414
相关链接
本文版权属于 Chem-Station化学空间， 欢迎点击按钮分享，未经许可，谢绝转载！
