概要
Satoh-Miura 反应 (Satoh-Miura reaction) 是各类芳香化合物或杂环芳香化合物在过渡金属催化剂 (主要涉及Rh催化剂[1]-[15]、Pd催化剂[16]-[19]、Co催化剂[20]、Ni催化剂[21]-[22]、Mn催化剂[23])存在下，通过双重C-H键活化过程，进行的区域选择性芳香同系化反应 (aromatic homologation reaction, 又称为去氢环化反应，dehydrogenative annulation或芳烃-炔苯环化，arene-alkyne benzannulation)。该反应由日本Osaka 大学工学部应用化学系 (大阪大学工学部応用化学科, Department of Applied Chemistry, Faculty of Engineering, Osaka University)的Satoh (佐藤 哲也, Satoh Tetsuya)与Miura (三浦 雅博, Masahiro Miura)研究室在2008年首次报道[1]。
Satoh-Miura 反应具有广泛的底物适用范围，中等至良好的反应收率与优良的原子经济性以及优良的区域选择性。这一反应的发展为芳烃同系化方法学的研究开辟了全新的途径[1]-[24]。目前，该反应已经广泛应用于一系列稠环芳烃与稠合芳香杂环分子[25]以及部分功能性高分子的构建[26]。因篇幅限制，这里小编只介绍Rh催化剂参与的Satoh-Miura 反应。对于其它过渡金属催化剂参与的Satoh-Miura 反应，小编将在下一期进行介绍。
基本文献
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参考文献
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反应实例
C-N轴手性N-芳基羟吲哚的合成[1]
2-萘基苯并咪唑与2-(1,2,3,4,5,6,7,8-八苯基蒽-9-基)苯并噁唑的合成[2]
2-苯基苯酚的芳香同系化[3]
聚(吡唑基萘)的合成[4]
实验步骤
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