本文作者：alberto-caeiro
澤村 正也(Masaya Sawamura), 日本有机化学家，现为北海道大学化学院教授，主要从事金属有机化学研究，图片：实验室主页。
经 历
- 1989, Kyoto University, Ph. D.;
- 1989, Kyoto University, Assistant Professor;
- 1993, Harvard University, Visiting Researcher;
- 1995, Tokyo Institute of Technology, Assistant Professor;
- 1995, The University of Tokyo, Assistant Professor;
- 1996, Hokkaido University, Lecturer;
- 1997, Hokkaido University, Associate Professor;
- 2001, Hokkaido University, Professor;
- 2016, Hokkaido University, Distinguished Professor.
获奖经历
- 1990, Eizai Award Synthetic Organic Chemistry, Japan;
- 1996, The Chemical Society of Japan Award for Young Chemists;
- 2007, OMCOS Poster Prize in Organometallic Chemistry;
- 2008, Visiting Lectureship Award from National Science Council, Taiwan;
- 2008, Asian Core Program (ACP) Lectureship Award;
- 2012, Chemical Society of Japan Award for Creative Work;
- 2012, Asian Core Program (ACP) Lectureship Award (2012);
- 2013, Asian Core Program (ACP) Lectureship Award (2013);
- 2014, Hokkaido University President’s Award for Outstanding Research;
- 2015, SSOCJ Nissan Chemical Industries Award for Novel Reaction and Method 2014;
- 2017, Nagoya Medal (Silver Medal);
- 2018, Negishi Award;
工作介绍
- 高选择性的烯丙基取代反应
烯丙基取代反应是合成化学中重要的有机反应之一。Sawamura教授实现了过渡金属钯或铜催化的立体专一性或对映选择性的烯丙基取代反应[1,2]。2018年，Sawamura教授实现了2-烷基吡啶的sp3C-H键不对称烯丙基化反应[2c]。
- 过渡金属催化的新反应研究
Sawamura教授主要研究铜和钯催化烯丙基取代反应，及铜催化的不对称加成反应[3]等。金属镍催化的偶联反应[4]，铱催化的不对称C-H键官能团化反应[5]等都有研究。
参考文献
- [1] For Palladium catalyzed reaction, see: a. Ohmiya, H. Makida, Y. Tanaka, T. Sawamura, M. J. Am. Chem. Soc., 2008, 130, 17276. DOI: 10.1021/ja808673n; b. Ohmiya, H. Makida, Y. Li, D. Tanabe, M. Sawamura, M. J. Am. Chem. Soc., 2010, 132, 879. DOI: 10.1021/ja9092264; c. Yasuda, Y. Ohmiya, H. Sawamura, M. Angew. Chem. Int. Ed., 2016, 55, 10816. DOI: 10.1002/anie.201605125;
- [2] For Copper catalyzed reaction, see: a. Ohmiya, H. Yokobori, U. Makida, Y. Sawamura, M. J. Am. Chem. Soc., 2010, 132, 2895. DOI: 10.1021/ja9109105; b. Yasuda, Y. Ohmiya, H. Sawamura, M. Angew. Chem. Int. Ed., 2016, 55, 10816. DOI: 10.1002/anie.201605125;
- [3] a. Schwarzer, M. C. Fujioka, A. Ishii, T. Ohmiya, H. Mori, S. Sawamura, M. Chem. Sci. 2018, 9, 3484. DOI: 10.1039/C8SC00527C; b. Ohmiya, H. Yoshida, M. Sawamura, M. Org. Lett. 2011, 13, 482. DOI: 10.1021/ol102819k; c. Ito, H. Ito, S; Sasaki, Y. Matsuura, K. Sawamura, M. J. Am. Chem. Soc. 2007, 129, 14856. DOI: 10.1021/ja076634o; d. Ito, H. Kosaka, Y. Nonoyama, K. Sasaki, Y. Sawamura, M. Angew. Chem., Int. Ed. 2008, 47, 7424. DOI: 10.1002/anie.200802342;
- [4] Nishizawa, A. Takahira, T. Yasui, K. Fujimoto, H. Iwai, T. Sawamura, M. Chatani, N. Tobisu, M. J. Am. Chem. Soc. 2019, 141, 7261. DOI: 10.1021/jacs.9b02751;
- [5] Reyes, R. L. Iwai, T. Maeda, S. Sawamura, M. J. Am. Chem. Soc. 2019, 141, 6817. DOI: 10.1021/jacs.9b01952.
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